Foxglove Plant: A Powerful Heart Tonic but can be Toxic

The foxglove plant is the perfect example of how the same plant can cure or kill. In the seventeenth century, in England, foxglove was given for the first time to an ill person suffering from heart-caused dropsy (edema in the whole body caused by heart failure). A few years later, the foxglove plant was included in the Edinburgh Pharmacopoeia.

From then on, much biochemical and biological research has been carried out on this plant, whose active components have not been substituted by any chemical product.

Presently, the foxglove plant glycosides are widely employed in medicine and have saved the lives of many people with heart-related issues. However, the foxglove plant is very toxic. An infusion with a minimum part of only one leaf (10 g) may cause an adult person’s death.

It is a problem of dosage. The therapeutic range is narrow, and the poisonous dose is very close to the medicinal one. Significant variations in the concentration of active components depend on where the plants grow, the gathering season, the drying time the plant takes, etc.

Pharmacological industries have isolated those active principles, making them chemically pure. Thus, it is easier to dose and apply them correctly. However, their effectiveness is lower because other substances usually present in the plant, which complement, do not appear together with chemically pure active components.

How to use Foxglove

1. Pharmaceutical preparations. The safest and most tolerated method to apply foxglove is to use its extract in pharmaceutical preparations. However, the complete plant’s use is more beneficial, though more caution is required to administer the correct dose. Only pharmacists and physicians with phytotherapy experience can benefit from this powerful plant. It can solve severe heart problems and even save lives if correctly applied.
2. Infusion. One gram of powder obtained from dry ground leaves per 100 ml of hot water. Steep for 15 minutes. Drink during the day, by spoonfuls. Do not exceed this dose. It must never be taken continuously for more than ten days because the glycosides accumulate in the body. Usually, it is taken for five days, with a two-day pause.

1. Compresses. Preparing an infusion with one or two leaves per liter of water, then soaking cotton cloths applied to the affected skin area.
2. Excellent wound healing agent: In external use, the leaves of the foxglove plant are a perfect wound healing agent for ulcers and skin wounds, including varicose ulcers. This was the main application of foxglove until its effects on the heart were discovered.

Foxglove Plant Scientific Facts

1. Synonym: Digitalis, dead men’s bells, dog’s fingers, fairy fingers, fairy gloves, finger flower, folks’ glove, lion’s mouth, ladies’ glove, purple foxglove, American foxglove.
2. French: Gant de Notre Dame, digitale.
3. Spanish: Digital, dedalera.
4. Habitat: Common in siliceous lands in the mountainous areas of Western Europe.
5. Description: Biennial plant of the Scrofulariaceae family, growing up to one and a half meters high. Large, velvet-like, lanceolate leaves grow from the plant’s lower part. Its flowers are finger-shaped, purple or pink colored, and grow from the of the stem.
6. Parts used: Leaves.

Healing Properties and Uses

Two kinds of substances may be distinguished in foxglove:

1. Non-glycosides: Digitoflavine (yellow coloring), cyclohexanol, malic and succinic acids, tannin, and an oxidizing diastase. Though these substances do not directly affect the heart, they complement and improve glycosides’ action.
2. Glycosides: They are responsible for the cardiotonic effects of the foxglove plant on the heart muscle. The most important ones are digoxin and digitalin. They have the following properties:
   – Increases strength of the heart contractions, improving its mechanical performance,
   – Balance the heartbeat rate when it is irregular or too quick.

For all these reasons, the glycosides of the foxglove plant are an indispensable remedy in cases of coronary insufficiency (inability of the heart to pump the blood needed in the body), which in acute cases is clinically shown as edema (soaking) of the lungs, or as dropsy (accumulation of liquid in the cavities and tissues of the body). Moreover, they balance the heartbeat rate and have specific diuretic action, which contributes to improving the circulatory system’s functioning.

WARNING: Though foxglove is a toxic plant, accidental intoxication is rare due to its disagreeable flavor. Chewing its leaves or flowers irritates the mouth and causes nausea, vomiting, vision alterations, bradycardia, and ultimately heart failure. A few flowers may cause death in a child.

First aid consists of stomach pumping, administering purgatives, activated charcoal, and urgent transportation of the afflicted person to a hospital.

DISCLAIMER: All content on this website is presented solely for educational and informational objectives. You should not rely on the information provided as a replacement for advice, diagnosis, or treatment from a qualified medical expert. If you are pregnant, nursing, or have any preexisting medical concerns, you should talk to your doctor before using any herbal or natural medicines.

REFERENCES

1. George D. Pamplona-Roger, M.D. “Encyclopedia of Medicinal Plants.” George D. Pamplona-Roger, M.D. Encyclopedia of Medicinal Plants. Ed. Francesc X. Gelabert. vols. 1 San Fernando de Henares: Editorial Safeliz, 2000. 221,222. Print. [foxglove plant]
2. https://www.sciencedaily.com/releases/2020/04/200413115908.htm
3. https://www.futurity.org/foxglove-plants-medicinal-compounds-heart-failure-2335522/