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Pedanius Dioscorides, the Greek physician, pharmacologist, botanist, and author (1st century A.D.), already warned that the flowers and leaves of the oleander plant are “deadly” poisonous for dogs, donkeys, mules, and many four-legged animals.” We can add that it is also toxic for humans.
The flowers and mainly the oleander leaves contain flavonic glycosides, rhutin, tannin, and resin. However, its most crucial active component is folinerin, a glycoside that, by hydrolysis, becomes aleandrigenin. This substance is a powerful cardiotonic, even more dynamic than the glycosides of foxglove. Nevertheless, its oral use is not recommended since the dosage is difficult to calculate, the therapeutic dose being very close to the toxic one.
In some Latin American countries, the oleander flowers are applied externally to combat scabies as cream or in poultices.
WARNING! Oleander is a poisonous plant. Eating only two leaves can be enough to kill an adult. In the case of poisoning, take the afflicted person to a hospital immediately.
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