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African natives used the root of the colombo plant as an essential remedy for diarrhea and dysentery. When the Portuguese settled in Mozambique and Madagascar in the seventeenth century, they discovered the plant and carried it to Europe. Currently, colombo is found in pharmacies worldwide as a component of several pharmaceutical preparations.
The root of the Colombo plant contains several alkaloids that chemically are similar to berberine (an alkaloid that is found in the barberry) and morphine; bitter components (columbine); and several inert substances (pectin, starch, and oxalate). It does not have tannin. Its properties are the following:
WARNING! When taken in high doses, it has toxic effects: nausea, vomiting, intestinal colic, and respiratory failure.
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